‘The product of four years of development, Alpha is an engine for answers. Its ambition is to delve into “all the knowledge in the world,” Wolfram says, to find and calculate information.
Though Alpha’s interface evokes Google ― whose co-founder Sergey Brin once spent a summer interning for Wolfram ― it’s more like the anti-Google.Type in a query for a statistic, a profile of a country or company, the average airspeed of a sparrow ― and instead of a series of results that may or may not provide the answer you’re looking for, you get a mini dossier on the subject compiled in real time that, ideally, nails the exact thing you want to know. It’s like having a squad of Cambridge mathematicians and CIA analysts inside your browser”….<More>
In July I linked to an article about chemicals that trick the body into losing weight and may even cure diabetes, looks like the science is gaining traction according to Scientific American “The drug works by triggering a protein called SIRT1 that normally kicks in during starvation and tells the body to burn fat and conserve energy, according to the study.
“We are activating the same enzymes that are activated when people go to the gym,” Peter Elliott, an exec at Sirtris Pharmaceuticals, the Glaxo arm that developed the drug, told Reuters……ood news for a human version of the medicine being developed to treat diabetes”…. <More>
“The tinier the active substance used, the easier it gets into places where it is intended to develop its effect.’
The calcium peroxide used in miniature form even penetrates into the tiniest of gaps and the interdental spaces, ensuring effective bleaching. Thanks to nano technology, SWISSDENT is able to generate an ideal result for your teeth with a small amount of bleach (0.1%), also permitting an extremely gentle and soft use”….<More>
“The new drugs are called sirtuin activators, meaning that they activate an enzyme called sirtuin. The basic theory is that all or most species have an ancient strategy for riding out famines: switch resources from reproduction to tissue maintenance. A healthy diet but with 30 percent fewer calories than usual triggers this reaction in mice and is the one intervention that reliably increases their life span.
But most people cannot keep to a diet with a 30 percent cut in calories, so a drug that could activate the famine reflex might be highly desirable. Dr. Leonard Guarente, an M.I.T. biologist who founded the field of sirtuin biology, thinks the famine reflex is mediated through the sirtuin enzymes. Dr. Sinclair, his former student, discovered that sirtuins could be activated by drugs. The most potent activator that emerged from his screens was resveratrol, a natural substance found in red wine, though in amounts probably too low to be significant for health.
“The Sirtris drug being tested in diabetic patients is a special formulation of resveratrol that delivers a bloodstream dose five times as high as the chemical alone. This drug, called SRT501, has passed safety tests and, at least in small-scale trials, has reduced the patients’ glucose levels.
The other drug is a small synthetic chemical that is a thousand times as potent as resveratrol in activating sirtuin and can be given at a much smaller dose. Safety tests in people have just started, with no adverse effects so far….resveratrol has doubled muscular endurance, lowered the bad form of cholesterol, protected against various bad effects of a high-fat diet and suppressed colon cancer. New reports are confirming some of these benefits, but others are ambiguous or puzzling. “…. <More>
“Just over a year ago DabbleDB launched, allowing people to create quick database driven applications with very few programming skills. Since then we’ve seen Zoho Creator, WyaWorks and Coghead launch their own competing applications. Salesforce AppExchange is arguably also a competitor, as are a number of other build-your-own-apps like Yahoo Pipes, Teqlo and Microsoft Popfly.
This is a crowded space, and there’s a reason for it. These tools let non-developers create useful and otherwise expensive applications for busineses that can be accessed directly or via the intranet. They can also be tailored to an infinite degree, giving companies more flexibility with off the shelf stuff. Most of these tools also allow for simple web application building as well, from simple web forms to more complicated, interactive applications.
LongJump, which launches today, is the newest entrant”…. <More>
“A recently published patent application discovered by MacRumors reveals that Apple is investigating the use of solar power in versions of their mobile devices — both handheld devices and portable computers…..Apple’s not the only one exploring this technology as an old (2001) Motorola patent describes the same technique”….. <More>
“One of the most encouraging signs that human limb regeneration is a feasible goal is the fact that our fingertips already have an intrinsic ability to regenerate. This observation was made first in young children more than 30 years ago, but since then similar findings have been reported in teenagers and even adults. Fostering regeneration in a fingertip amputation injury is apparently as simple as cleaning the wound and covering it with a simple dressing. If allowed to heal naturally, the fingertip restores its contour, fingerprint and sensation and undergoes a varying degree of lengthening. The success of this conservative treatment of fingertip amputation injuries has been documented in medical journals thousands of times”…. <More>